Webster's Revised Unabridged Dictionary · 1913

Orthopnoa

Orthopnoa , noun

[Latin orthopnoea, Greek {not transcribed}; 'orqo`sstraight, right + pnei^n to breathe: compare French orthopnée.]

(Medicine) Specifically, a morbid condition in which respiration can be performed only in an erect posture; by extension, any difficulty of breathing.

Also: Orthopny, Orthopnoea