Webster's Revised Unabridged Dictionary · 1913

inactivate

inactivate , transitive verb

to make inactive; as, boiling will inactivate most enzymes; acetylation of the antibiotic inactivated it.

To inactivate an enzyme or chemical usually renders it permanently inactive; to inactivate a machine (as by turning a switch) may be reversible, and for machines and devices, the term deactivate is usually used. The distinction is worth preserving.