Webster's Revised Unabridged Dictionary · 1913

Handcuff

Handcuff (-kuf`) , noun

[Anglo-Saxon handcops; hand hand + cosp, cops, fetter. The second part was confused with English cuffs,]

A fastening, consisting of an iron ring around the wrist, usually connected by a chain with one on the other wrist; a manacle; -- usually in the plural.

Handcuff (hand"kuf`) , transitive verb

To apply handcuffs to; to manacle. — Hay (1754)