Exasperation
Exasperation , noun
[Latin exasperatio: compare French exaspération.]
1.
The act of exasperating or the state of being exasperated; irritation; keen or bitter anger.
Extorted from him by the exasperation of his spirits.
2.
Increase of violence or malignity; aggravation; exacerbation.
Exasperation of the fits.