Exacerbation
Exacerbation (egz*as`ẽr*bā"shun) , noun
[Compare French exacerbation.]
1.
The act of rendering more violent or bitter; the state of being exacerbated or intensified in violence or malignity; as, exacerbation of passion.
2.
(Medicine) A periodical increase of violence in a disease, as in remittent or continuous fever; an increased energy of diseased and painful action.