Webster's Revised Unabridged Dictionary · 1913

despond

despond , intransitive verb

[Latin despondēre, desponsum, to promise away, promise in marriage, give up, to lose (courage); de- + spondēre to promise solemnly. See Sponsor.]

To give up the will, courage, or spirit; to be thoroughly disheartened; to lose all courage; to become dispirited or depressed; to take an unhopeful view.
I should despair, or at least despond. — Scott's Letters
Others depress their own minds, [and] despond at the first difficulty. — Locke
We wish that... desponding patriotism may turn its eyes hitherward, and be assured that the foundations of our national power still stand strong. — D. Webster

Despond , noun

Despondency. [Obsolete]
The slough of despond. — Bunyan