Webster's Revised Unabridged Dictionary · 1913

Depravation

Depravation (dep`rȧ*vā"shun) , noun

[Latin depravitio, from depravare: compare French dépravation. See Deprave.]

1.
Detraction; depreciation. [Obsolete]
To stubborn critics, apt, without a theme, For depravation. — Shakespeare
2.
The act of depraving, or making anything bad; the act of corrupting.
3.
The state of being depraved or degenerated; degeneracy; depravity.
The depravation of his moral character destroyed his judgment. — Sir G. C. Lewis
4.
(Medicine) Change for the worse; deterioration; morbid perversion.